Drug-eluting Ti wires with titania nanotube arrays for bone fixation and reduced bone infection

Drug-eluting Ti wires with titania nanotube arrays for bone fixation and reduced bone infection

Current bone fixation technology which uses stainless steel wires known as Kirschner wires for fracture fixing often causes infection and reduced skeletal load resulting in implant failure. Creating new wires with drug-eluting properties to locally deliver drugs is an appealing approach to address some of these problems. This study presents the use of titanium [Ti] wires with titania nanotube [...

Bioactive SrTiO(3) nanotube arrays: strontium delivery platform on Ti-based osteoporotic bone implants.

Development of strontium releasing implants capable of stimulating bone formation and inhibiting bone resorption is a desirable solution for curing osteoporosis. In this work, well-ordered SrTiO(3) nanotube arrays capable of Sr release at a slow rate and for a long time are successfully fabricated on titanium by simple hydrothermal treatment of anodized titania nanotubes. This surface architect...

Characterization of drug-release kinetics in trabecular bone from titania nanotube implants

PURPOSE The aim of this study was to investigate the application of the three-dimensional bone bioreactor for studying drug-release kinetics and distribution of drugs in the ex vivo cancellous bone environment, and to demonstrate the application of nanoengineered titanium (Ti) wires generated with titania nanotube (TNT) arrays as drug-releasing implants for local drug delivery METHODS Nanoeng...

Effect of Ti defects on electrochemical properties of highly-ordered titania nanotube arrays

Interaction of Au with titania: the role of reduced Ti

The interaction of Au with oxide supports has been found to play a vital role in determining the unique properties of Au catalysts. In this study, the binding of Au with titania was investigated using scanning tunneling microscopy (STM) and ultra-violet photoemission spectroscopy (UPS). Two support systems, rutile TiO2(110) and an ordered TiOx/Mo(112) thin film were used. On a highly defective ...